What Is Ariessence (PDGF) and Why Do People Need It with Microneedling?

An expert guide for patients in Kennebunk, Maine, who want healthier, more youthful skin with natural-looking results.

Modern aesthetic medicine has shifted dramatically over the last decade. Instead of aggressive procedures with long downtime, today’s patients want skin regeneration—treatments that stimulate the body’s own healing processes to create healthier, stronger skin.

One of the most exciting advancements in this field is the combination of microneedling with Ariessence (PDGF), a powerful regenerative solution designed to enhance the results of microneedling treatments.

Patients often ask:

• What exactly is Ariessence (PDGF)?

• Why is Ariessence (PDGF) used with microneedling?

• Is it better than traditional microneedling alone?

• Does it really improve skin rejuvenation results?

If you’ve been curious about Ariessence (PDGF) or want to understand why it’s becoming a preferred treatment among aesthetic professionals, this comprehensive guide will explain everything you need to know.

For patients in and around Kennebunk, ME who want natural-looking skin rejuvenation without long downtime, Ariessence (PDGF) paired with microneedling may be one of the most effective treatments available today.

The Growing Demand for Natural Skin Rejuvenation

Many people reach their late 30s, 40s, and 50s and begin noticing subtle but frustrating changes in their skin.

Common concerns include:

• Fine lines and wrinkles

• Dull or uneven skin tone

• Sun damage and pigmentation

• Thinning skin

• Acne scars

• Enlarged pores

• Loss of collagen and elasticity

While injectables and lasers can address some of these issues, many patients prefer treatments that improve the quality of their skin itself without a big price tag and downtime.

This is where microneedling and regenerative skin therapies come into play.

Microneedling has long been known as one of the most effective minimally invasive treatments for stimulating collagen production. However, when paired with advanced regenerative solutions like Ariessence (PDGF), its results can become even more powerful.

What Is Ariessence?

Ariessence PDGF (Platelet Derived Growth Factor) is powered by the only proven growth factor available in aesthetics, driving rapid skin rejuvenation.  Ariessence pure PDGF+ is a potent, cutting-edge, post-treatment enhancement that provides patients with a faster healing process as well as naturally beautiful, healthier-looking skin. 

We combine the benefits of one of the body’s most potent growth factors for skin rejuvenation, PDGF-BB, with the soothing hydration of pure hyaluronic acid. When used following treatments, including microneedling, RF microneedling, laser skin resurfacing, especially CO2, and peels, Ariessence pure PDGF+ can enhance patients’ results and reduce downtime.

When applied during microneedling, Ariessence (PDGF) penetrates deep into the skin through microscopic channels created by the treatment.

This allows the regenerative ingredients to work directly within the skin, where they can:

• Stimulate collagen production

• Improve cellular repair

• Enhance skin texture and tone

• Support faster recovery

• Amplify overall treatment results

Rather than simply hydrating the skin’s surface, Ariessence (PDGF) works at a cellular level to promote true skin regeneration.

Understanding Microneedling

To understand why Ariessence (PDGF) is so effective, it’s important to first understand how microneedling works.

Microneedling is a minimally invasive treatment that uses tiny, sterile needles to create controlled micro-injuries in the skin.

These microscopic channels trigger the body’s natural healing response.

When the skin begins to repair itself, it produces:

• New collagen

• Elastin fibers

• Healthy skin cells

Over time, this process improves:

• Skin texture

• Skin tone

• Elasticity

• Fine lines and wrinkles

• Acne scars

• Overall skin quality

Microneedling alone is already a powerful treatment—but pairing it with regenerative solutions like Ariessence (PDGF) allows the treatment to work even more effectively.

Why Ariessence (PDGF) Is Used with Microneedling

Microneedling creates thousands of tiny channels in the skin. These channels provide an ideal pathway for powerful regenerative ingredients to reach deeper layers of tissue.

When Ariessence (PDGF) is applied during the procedure, it can penetrate the skin far more effectively than topical products applied to intact skin.

This combination allows the treatment to work in two ways simultaneously:

1. Mechanical stimulation from microneedling

The micro-injuries trigger collagen production and cellular repair.

2. Biological stimulation from Ariessence (PDGF)

Growth factors and regenerative molecules support healing and accelerate skin rejuvenation.

Together, these mechanisms create a powerful regenerative environment within the skin. It can be used after lasers as well to help with healing. 

The Science Behind Ariessence (PDGF)

Ariessence pure PDGF+ is a potent, proprietary, topical, post-procedural enhancement that utilizes recombinant technology to produce a pure, sterile, pharmaceutical-grade PDGF combined with hyaluronic acid. HA acts to retain or increase moisture, as a skin conditioning agent, and as a contributor to a healthy skin barrier.  

Growth Factors

Growth factors are naturally occurring proteins that regulate cellular growth, repair, and regeneration.

They play a critical role in:

• Collagen production

• Skin healing

• Tissue repair

When introduced during microneedling, growth factors help amplify the skin’s natural regenerative response.

Clients create a regenerative environment that enhances the skin’s ability to heal and rebuild. 

The science behind PDGF is supported by over 1,000 published papers and more than 100+ clinical trials, including an extensively studied safety profile. PDGF is widely used in wound healing, orthopedics, and dentistry. 

Key Benefits of Ariessence (PDGF) with Microneedling

Patients who combine Ariessence (PDGF) with microneedling often experience enhanced results compared to microneedling alone.

Here are some of the most notable benefits.

Improved Collagen Production

Collagen is the structural protein responsible for keeping skin firm, smooth, and youthful.

Unfortunately, collagen production begins to decline in our mid-20s and continues to decrease with age.

Microneedling stimulates collagen production naturally, but Ariessence (PDGF) helps support and amplify this process, leading to stronger and more noticeable improvements in skin structure.

Faster Skin Recovery

One of the major advantages of regenerative therapies is improved healing.

Because Ariessence (PDGF) contains ingredients that support cellular repair, many patients experience faster recovery after microneedling treatments.

This means:

• Reduced redness

• Shorter healing time

• Quicker return to normal activities

For busy professionals and parents in Kennebunk, ME, this can make a significant difference.

Enhanced Skin Texture

Microneedling is widely known for improving rough skin texture and acne scars.

When combined with Ariessence (PDGF), the treatment can produce smoother, more refined skin by encouraging healthier cell turnover and regeneration.

Brighter, Healthier Skin

Many patients notice that their skin looks brighter and more radiant after treatment.

This is because regenerative therapies help improve circulation, cellular repair, and overall skin health.

Natural-Looking Results

One of the biggest reasons patients choose microneedling with Ariessence (PDGF) is that it produces natural improvements rather than dramatic cosmetic changes.

Your skin simply looks healthier, smoother, and more youthful.

There are no obvious signs that you’ve had a cosmetic procedure.

Ariessence (PDGF) vs PRP, PRF, and Other Microneedling Add-Ons

You may have heard of other treatments used with microneedling, such as platelet-rich plasma (PRP) and the newer platelet-rich fibrin (PRF), which is what we offer at Everglow.

PRP and PRF use the patient’s own blood to extract growth factors that are then applied to the skin during treatment.

While these can be effective, Ariessence (PDGF) offers several advantages:

Consistency

PRF quality can vary significantly depending on the patient’s health, hydration, and platelet levels.

Ariessence (PDGF) provides consistent concentrations of regenerative factors in every treatment.

Convenience

PRF requires a blood draw and processing time before treatment.

Ariessence (PDGF) does not require blood collection, making the treatment faster and more convenient.

Advanced Formulation

Ariessence (PDGF) contains the same growth factors every time.  The dose is consistent, and at least 30,000 times more potent than your own growth factors in PRF. 

Who Is a Good Candidate for Ariessence (PDGF) and Microneedling?

This treatment is ideal for patients who want natural skin rejuvenation without downtime.

You may be a good candidate if you want to improve:

• Fine lines and wrinkles

• Acne scars

• Skin texture

• Sun damage

• Dull skin tone

• Early signs of aging

It is also a great option for patients who want preventative skin maintenance to keep their skin healthy as they age.

What to Expect During Treatment

A typical microneedling session with Ariessence (PDGF) is relatively quick and comfortable.

Consultation

Before treatment, your provider will evaluate your skin and discuss your goals to determine whether the procedure is right for you.

Preparation

A topical numbing cream is applied to ensure comfort during the treatment.

Microneedling Procedure

A specialized microneedling device (we use the Toskani Exceed device) creates controlled microchannels in the skin.

During this process, Ariessence (PDGF) is applied so it can penetrate deeply into the skin.

Treatment Time

The entire appointment typically takes about 45 to 60 minutes.

Recovery and Downtime

One of the reasons microneedling with Ariessence (PDGF) is so popular is the minimal downtime.

Most patients experience:

• Mild redness similar to a sunburn

• Slight sensitivity for 24–48 hours

• Light flaking or dryness

Most people feel comfortable returning to normal activities the next day.

How Many Treatments Are Needed?

While some improvement can be seen after a single treatment, most patients achieve the best results with a series of treatments.

A typical treatment plan includes:

• 2 to 4 sessions spaced several weeks apart

This allows collagen production to build gradually for long-lasting improvements.

Why Professional Expertise Matters

Microneedling may sound simple, but achieving the best results requires skill, knowledge, and proper technique.

An experienced provider understands how to:

• Customize needle depth

• Adjust treatment intensity

• Choose the right regenerative products

• Develop a personalized treatment plan

For patients in Kennebunk, ME seeking professional skin rejuvenation, working with a trained aesthetic specialist ensures both safety and optimal results.

The Future of Regenerative Aesthetics

The aesthetics industry is increasingly moving toward regenerative treatments that support the body’s natural healing processes.

Instead of relying solely on fillers or aggressive procedures, these treatments focus on improving skin quality at the cellular level.

Ariessence (PDGF) represents an exciting advancement in this field.

By combining regenerative science with microneedling, patients can achieve:

• Healthier skin

• Stronger collagen support

• Natural-looking rejuvenation

• Minimal downtime

Final Thoughts

Healthy, youthful skin is not just about treating wrinkles—it’s about improving the underlying health of the skin itself.

Microneedling has long been one of the most effective treatments for stimulating collagen production. When enhanced with Ariessence (PDGF), the results can become even more powerful.

This combination allows patients to achieve smoother, brighter, and healthier skin through advanced regenerative science.

For individuals in Kennebunk and the surrounding coastal communities who want subtle yet meaningful improvements in their skin, microneedling with Ariessence (PDGF) offers a modern solution.

Ready to Experience the Benefits of Ariessence (PDGF) and Microneedling?

If you’re curious whether Ariessence (PDGF) with microneedling is right for your skin, the best next step is a personalized consultation.

During your appointment, we’ll evaluate your skin, discuss your goals, and create a customized treatment plan designed to help you achieve natural, healthy skin rejuvenation.

Schedule your appointment today.

Your skin deserves expert care—and regenerative treatments like Ariessence (PDGF) may be the key to revealing your healthiest, most radiant skin yet.