Rebuilding Volume Loss Naturally with Sculptra® and Radiesse®

Your guide to biostimulators, collagen, and natural anti-aging at Everglow, a Medspa in Kennebunk, Maine

If you’ve looked in the mirror lately and thought, “I still feel like me—I just wish my face had a little more support,” you’re in the right place. Midlife doesn’t need a hard rebrand; it needs smart, natural anti-aging approaches that rebuild what time gradually thins (collagen, elastin, and structural volume) without surgery, “overdone” results, or weeks of downtime.

At Everglow Medical Aesthetics, your neighborhood medspa in Kennebunk, we specialize in treatments that work with your biology, not against it. Two heavy-hitters we reach for every day: Sculptra® and Radiesse®. These are biostimulators—injectables that help your skin make more of its own firming matrix over time, so your results look like you, just quietly refreshed.

This deep-dive is your friendly, expert guide. We’ll cover how biostimulators differ from traditional fillers, what to expect with Sculptra and Radiesse, who they’re for, and which treatments pair beautifully with them (from neuromodulators to skin-tightening and resurfacing). We’ll also weave in practical “biohacking” habits that support collagen long-term, because great results start in the treatment room but last in everyday life.

Along the way, we’ll keep the science clear, the language warm, and the plan actionable.

Why faces lose volume as we age

Volume loss isn’t “one thing”—it’s a blend of changes in bone, deep fat pads, skin thickness, and collagen. Over time, facial fat compartments shift, bone subtly remodels, and skin produces less collagen and elastin. The result? Softer midface support, flatter cheeks, deepening folds, and skin that doesn’t “bounce back” like it used to.

You’ll feel it (makeup sits differently, your jawline’s less defined) and you’ll see it (photo angles you loved suddenly… don’t). The good news: we can gently and naturally rebuild by asking your own skin to do what it does best: make collagen.

Biostimulators 101: Sculptra® & Radiesse® (and how they’re different from hyaluronic acid fillers)

Most clients know hyaluronic acid (HA) fillers (great for shape, contour, and instant polish). Biostimulators are different. Instead of simply placing volume, they stimulate your body to create new collagen over weeks to months. That’s why results look so believable—your own tissue is doing the work.

• Sculptra® uses poly-L-lactic acid (PLLA)—microparticles that kickstart your fibroblasts to make collagen and improve skin quality over time. sculptrausa.com

• Radiesse® uses calcium hydroxylapatite (CaHA) microspheres—first providing immediate support, then prompting new collagen (and elastin) as its gel carrier gradually resorbs.  https://radiesse.com/

Think of biostimulators as a collagen savings plan. You contribute now; the returns compound later.

Sculptra®: the collagen “campfire” that builds gradually

What it is:

Sculptra is an FDA-approved, biostimulatory injectable made of PLLA. Once placed, PLLA works as a framework that encourages your skin to replenish collagen—improving firmness, smoothness, and facial support with a very natural look. sculptrausa.com

How it works:PLLA microparticles act like tiny signals that say, “Rebuild here.” Your body responds by laying down fresh collagen around the particles. As PLLA is metabolized, your own collagen remains—subtle at first, then gradually more visible over weeks to months.

Where we use it:Commonly, the midface/cheeks, temples, jawline, and lower face to restore lost support and soften folds, especially when you want improvement that doesn’t announce itself overnight.

What to expect:

• Number of sessions: A series is typical (often 2–3 sessions several weeks apart) to build a smooth, cohesive result. Galderma

• Timeline: Early softness gives way to noticeable improvement as collagen matures (think 6–12 weeks).

• Longevity: Results may last up to two years when the series is completed and maintained. Galderma

• Aftercare: Sculptra’s official FAQ suggests the 5-5-5 massage rule—massage the treated areas for 5 minutes, 5 times a day, for 5 days to help distribute product evenly. We’ll teach you exactly how. sculptrausa.com

Why our clients love it:

• Natural anti-aging: It’s your own collagen creating the lift and firmness.

• Skin quality bonus: Clients notice a “thicker,” healthier feel to the skin over time.

• Low-key glow up: Gradual change that your friends read as “rested” and “refreshed.”  We all love that “Sculptra Glow” you’ll get!

The science corner (for the curious):PLLA has been shown to increase collagen gene expression and synthesis in fibroblasts—one reason Sculptra’s effects build and persist. PMC+1

Good to knowSculptra is not a lip filler and isn’t placed close to mucosal surfaces; we’ll guide candidacy and technique to minimize risks and maximize outcomes. (We’ll cover safety shortly.)

Radiesse®: instant lift now, collagen support later

What it is:Radiesse is a CaHA gel that provides immediate structural support, then stimulates collagen (and elastin) as the carrier gel resorbs—delivering both short- and long-term benefits. It can be used as a filler, or we use it more as a biostimulator by diluting it with saline.  When we do this it is referred to as either dilute Radiesse or hyper-dilute Radiesse.  

How it works:The CaHA microspheres create a scaffold that recruits fibroblasts and triggers neocollagenesis. As the gel dissipates, your newly formed collagen takes over, supporting smoother, firmer contours. Radiesse Injectables

Where we use it:

• Lower face contouring (jawline, marionette lines)

• Midface support (cheek definition)

• Hands (FDA-approved for hand augmentation to correct volume loss) Radiesse Injectables

• Hyperdilute Radiesse (mixed with saline/lidocaine) for skin quality and mild laxity in the neck, décolletage, face, and hands—think firmer, finer-grained skin over time. merzaesthetics.ca

What to expect:

• Immediate improvement (thank you, gel support) plus progressive collagen and elastin gains over the following months. Radiesse Injectables

• Longevity: Commonly one year or more, depending on area, dose, and your metabolism. Radiesse Injectables

Why our clients love it:

• Two-phase payoff: A quick “I can see it” lift and the longer arc of collagen for durability.

• Versatility: From sculpting a jawline to rejuvenating crepey neck or hands (with hyperdilute technique).

• Skin quality: Evidence suggests increases in collagen and elastin, and even improved dermal architecture. PMC

Sculptra vs. Radiesse: how we choose (or combine) for natural anti-aging

Both are biostimulators that fit beautifully into a natural anti-aging plan. Here’s how we think through your personalized approach at our Everglow Kennebunk medspa:

Choose Sculptra when you want...

• The most believable, gradual improvement (no “overnight” jump)

• A focus on global support and skin quality across the face

• A “collagen-first” rebuild with long arc maintenance (often up to 2 years) Galderma

Choose Radiesse when you want…

• Instant structure plus long-term collagen payoff Radiesse Injectables+1

• Lower-face definition (jawline/marionettes) or hand rejuvenation (on-label) Radiesse Injectables

• Hyperdilute options to firm and smooth thin or crepey skin merzaesthetics.ca

Choose both when you want…

• A staged, layered result—e.g., Sculptra for foundational support + Radiesse to sharpen a jawline or refine the lower face or improve skin quality

• Strategic pairing with energy-based devices (keep reading) for lift + skin quality in tandem

We’ll map your unique anatomy, goals, timeline, and event calendar to design the best plan, not just a plan.  Some patients are better suited to one or the other, and we can determine that at a complementary consultation. They are priced similarly.

Treatments that pair perfectly with biostimulators

Biostimulation plays the long game. Pair it with the right “accelerators” and you’ll enjoy both near-term polish and long-term resilience.  Keep in mind, we always want to use lasers and energy devices before we do injectables.  

1) Hyaluronic Acid (HA) Fillers — for micro-refinements

When we want to add precision contour (a lip edge, a soft tear trough, a little lift at the cheek apex), HA fillers are unbeatable, and reversible if needed. Biostimulators set the foundation; HAs finesse the finish.

2) Neuromodulators — for expression lines

Softening the dynamic lines (glabella, forehead, crow’s feet, DAO, masseter if appropriate) allows your new collagen to shine without being creased repeatedly.

3) Skin-tightening (e.g., ultrasound or RF)

Pair your collagen rebuild with non-invasive tightening to subtly lift and firm where laxity hides your structure. This combo often gives that coveted “snatched but not obvious” result.

4) RF Microneedling — texture + firmness

RF microneedling promotes neocollagenesis in the dermis. Stacking it with biostimulators can amplify skin quality—think smoother texture, finer pores, and better snap.

5) Laser resurfacing (fractional or non-ablative)

Great for tone, texture, and fine lines. If pigmentation and dullness are stealing radiance, a gentle resurfacing plan can restore the glow while Sculptra/Radiesse rebuilds from beneath.

6) Skin quality injectables + skincare

Consider skin boosters for hydration and luminosity, then anchor your home routine with SPF, retinoids, vitamin C, and barrier-friendly moisturizers. The “short list” works—and it multiplies the value of your in-office plan.

Biohacking your collagen (without going overboard)

We love a good gadget—but the most effective biohacking for collagen is delightfully simple and sustainable:

• Protein on purpose: Aim for protein at each meal; collagen is a protein and your fibroblasts need amino acids to build.

• Vitamin C daily: Critical cofactor for collagen synthesis (your skincare and your plate).

• Sun strategy: Daily broad-spectrum SPF. UV is the fastest way to burn down your collagen “savings.”

• Retinoids at night: The evidence-based way to boost cell turnover and support dermal remodeling.

• Sleep + stress: Collagen is remodeled while you rest. Stress management (walks, breathwork) helps keep cortisol from working against your skin.

• Strength training: Lean muscle supports posture and facial dynamics; better circulation = better glow.

Small, repeatable steps → bigger, longer-lasting gains.

Your visit to Everglow Medical Aesthetics (Kennebunk, ME)

1) Collaborative consultWe’ll talk through what you see, what you feel, and what you want friends to notice (“You look great—did you go on vacation?”). We’ll map facial vectors, skin thickness, and structural priorities.

2) A layered plan (not a one-off)Most beautiful results come from sequencing: biostimulator foundation → precision HA micro-tweaks → skin-tightening/resurfacing → maintenance. We’ll also plan around trips, events, and seasons.

3) The appointmentWe prioritize comfort (topicals, local anesthetics where appropriate), safety, and artistry. We favor cannulas (safer, less bruising) strategically and inject in small, thoughtful aliquots to keep things even and smooth.

4) Aftercare

• With Sculptra, you’ll follow the 5-5-5 massage routine (we’ll demonstrate). sculptrausa.com

• With Radiesse, we’ll give tailored guidance depending on whether we use it diluted (structure) or hyperdiluted (skin quality). merzaesthetics.ca 

• Expect normal, temporary swelling or tenderness; avoid intense exercise for the first 24 hours, and follow your personalized instructions.

5) Follow-ups & longevity We’ll photograph progress and schedule touchpoints so we can build, then maintain—not ping-pong between “too much” and “not enough.”

FAQ: timelines, longevity, safety, and more

How soon will I see results?

• Sculptra: Changes are gradual as collagen forms; best seen from 6–12 weeks onward, compounding after each session. Galderma

• Radiesse: Expect immediate softening/lift from the gel plus continued improvement as collagen builds over months. Radiesse Injectables

How long do results last?

• Sculptra results can last up to two years after a completed series, with maintenance. Galderma

• Radiesse typically lasts a year or more, depending on the area and dose. Radiesse Injectables

Are these treatments “natural”? They’re as natural-looking as it gets because they stimulate your own collagen rather than relying solely on placed volume. Technique matters; conservative, well-placed product plus time equals believable results. sculptrausa.com+1

Are Sculptra and Radiesse the same as filler? They’re different from standard HA fillers. Both are biostimulators; Sculptra (PLLA) and Radiesse (CaHA) create structural improvement by triggering your collagen. (Radiesse also offers immediate gel support.) sculptrausa.com+1

Can Sculptra or Radiesse be dissolved? Unlike HA fillers (which can be dissolved with hyaluronidase), Sculptra and Radiesse are not “reversible” on demand—another reason to seek an experienced injector who favors conservative, layered dosing.

What about side effects or risks? As with any injectable, bruising, swelling, and tenderness are common and temporary. Rarely, nodules or irregularities can form (proper dilution, placement, massage, and follow-up reduce this risk). We’ll review your medical history, indications, and all aftercare before treatment. (Radiesse and Sculptra have robust safety and mechanism data; ask us to share the full IFU/PI in clinic.) Radiesse Injectables+1

Where can Radiesse be used on-label? For facial wrinkles/folds, jawline contour in adults (Radiesse +), and hand augmentation to correct volume loss. We’ll discuss on- vs. off-label approaches in your consult. Radiesse Injectables

Do I need to massage after Sculptra? Yes—Sculptra’s own FAQ recommends the 5-5-5 massage rule to help distribute the product uniformly. We’ll show you exactly how to do it. sculptrausa.com

Will I look “done”? Our ethos is natural anti-aging—quiet, confident, and appropriate for your features. We prefer subtle, layered improvements and photos to verify symmetry and restraint at every step.

Real-world plans our clients love (examples)

Goal: “I want my cheeks back and my smile lines softer—but I don’t want anyone to know.”

• Approach: 2–3 sessions of Sculptra to rebuild foundational support → micro-HA in the smile line shadows → RF microneedling for texture.

• Why it works: Sculptra restores that “pillow” under the skin; tiny HA touches what Sculptra shouldn’t; RF smooths the surface.

Goal: “My jawline used to be sharp. Now it’s… soft.”

• Approach: Radiesse for lower-face definition (undiluted) → optional hyperdilute Radiesse for crepey neck → neuromodulator for masseter (if clenching plays a role). Radiesse Injectables+1

• Why it works: Instant structure plus a collagen plan to hold the line.

Goal: “My hands give away my age more than my face.”

• Approach: Radiesse in the dorsum of hands (on-label), followed by topicals and sun protection. Radiesse Injectables

• Why it works: Restores soft-tissue cushion and improves crepey look.

A deeper science note (for enthusiasts)

• PLLA (Sculptra): Studies show upregulation of collagen gene expression in fibroblasts; as particles degrade, collagen remains. PMC+1

• CaHA (Radiesse): Clinical literature demonstrates neocollagenesis and neoelastogenesis, with histology revealing increases in collagen I/III and elastin over time; that’s the basis for its immediate + long-term profile.  Safer option for those with autoimmune issues.  PMC+1

Why choose a Medspa in Kennebunk (and why Everglow by Robyn)

• Local, personalized care: We know the pace of life in southern Maine. Your plan respects school schedules, travel, and seasons.

• Artist + clinician: The most natural results come from dose discipline, vector mapping, and an eye for proportion.

• Layered philosophy: Foundational collagen, precise contour, then skin quality—never “one-and-done.”

• Safety first: Product selection, dilution, depth, and aftercare are as important as where the needle goes. We teach you everything we do.

Your at-home “natural anti-aging” checklist

• Morning: Vitamin C serum → moisturizer → broad-spectrum SPF

• Evening: Retinoid (as tolerated) → nourishing moisturizer

• Weekly: Gentle exfoliation or hydrating mask

• Daily: Protein at each meal, hydration, sun sense

• Weekly (bonus): Light strength training + a walk outside (hello, mood and microcirculation)

Stack these with your in-office biostimulators and you’ve got a biohacking plan that’s realistic—and potent.

Ready to rebuild—naturally?

If you’re craving natural anti-aging, quiet confidence, and skin that feels supported again, Sculptra® and Radiesse® are exceptional tools—especially when layered with the right refinements. Let’s design your plan together here in Kennebunk.

Book your appointment online here and ask for a Consult—we’ll take it from there.  If you’re ready to go, book a Biostimulator appointment.